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Reply To: Nutrients and supplements of various nature that shouldn't be taken together

ferum — Sun, 02 Apr 2023 05:22:04 +0000

Magnesium, calcium and multivitamins:
If you take magnesium, it is not recommended to take it at the same time as your multivitamins. Magnesium may interfere with the absorption of other minerals found in the multivitamins, like iron and zinc. Additionally, it is not recommended to taking calcium, magnesium or zinc together, because these compounds will “compete for absorption.” Calcium may also prevent the absorption of iron. Also, while taking calcium and magnesium may help to prevent development of osteoporosis, in order to maximize the benefits, it can be recommended to take them at least some two hours apart.

Vitamins D, E and K:
Some studies have shown that absorption of Vitamin K may be reduced when other fat-soluble vitamins such as Vitamin E and Vitamin D are taken together. Similar advice can be given – take these vitamins at least two hours apart to maximize their absorption.

Additional list of incompatibilities:
– Fish Oil & Gingko Biloba – both have blood-thinning potential, therefore the effect can be compounded and potentially result in uncontrollable bleeding or inability to clot.
– Copper and zinc – If one must take both, take them at least two hours apart.
– Iron and Green tea – Skip green tea on days when you’re taking your iron supplements.
– Vitamin C and B12 – some studies have shown that Vitamin C could break down Vitamin B12 in one’s digestive tract, thus reducing B12 absorption. Recommendation – wait at least two hours before taking them.

Conclusion:
Taking supplements properly, can a very daunting task.

Reply To: Nutrients and supplements of various nature that shouldn't be taken together

ferum — Sun, 02 Apr 2023 03:38:32 +0000

Here are some of the examples:
– St. John’s Wort speeds up metabolism of oral contraceptives resulting in decreased amount of hormones in OCs which are absorbed.
– Excessive consumption of grapefruit or drinking grapefruit juice could impact the amount of many medications, including OCs that the body absorbs.
– Activated charcoal may bind to OC hormones in the gut and thus render them ineffective.
– Soy products, such as tempeh and tofu contain isoflavones which are a type of phytoestrogen. Phytoestrogens can potentially impact the estrogen in birth control. However, more research is needed to determine the effects of phytoestrogens on birth control.
When on birth control, it is strongly advised to discuss one’s goals of taking supplements, including vitamins and minerals, with the doctor prescribing the specific OCs.

Reply To: Nutrients and supplements of various nature that shouldn't be taken together

ferum — Sun, 02 Apr 2023 03:34:50 +0000

Some of the vitamins and supplements may interact with oral contraceptives (OCs) and thus reduce the effectiveness of desired birth control.

Nutrients and supplements of various nature that shouldn't be taken together

ferum — Sun, 02 Apr 2023 03:22:10 +0000

Today, based on scientific research and clinical studies, we know that not all of the nutrients that we consume, be it in the form of specific foods or as supplements, are absorbed by the body with equal efficiencies. Some of the otherwise healthy compounds, may simply compete for the absorption and some may even result in adverse interactions, which can be harmful to one’s health.
This discussion thread is to point out such known incompatibilities and I will start with a few examples. However, I am not claiming to be an expert in this field myself, these are just a small collection of statements by professionals.

Shilajit/Mumijo – Conqueror of mountains, rocks, Destroyer of Weakness

densel — Sat, 01 Apr 2023 05:45:54 +0000

Shilajit is a natural substance found mainly in the Himalayas, Badakhshan- Afghanistan, Karakoram, Gilgit-Baltistan – Pakistan, Nepal, Bhutan, Russia, Central Asia, Iran, Mongolia and in the south of Peru. This resin-like substance is formed for centuries by the gradual decomposition of certain plants by
the action of microorganisms.

Lifespan study of cultured fibroblasts with mitochondrial pertubations

ferum — Wed, 15 Mar 2023 02:41:17 +0000

Study aims to provide a complementary (to other model systems) strategy and research model to conduct lifespan experiments in cultured human fibroblasts. This research team focused on mitochondrial metabolism in order to better understand how cellular energetics affect the biology of cellular aging. Special emphasis was made on longitudinal dataset collection – for the purpose of modeling cellular aging process in time.
The dataset (multi-omics) included genomic, epigenomic, transcriptomics, and protein-based measurements, along with the bio-energetic and mitochondrial OxPhos (mitochondrial oxidative phosphorylation system) measurements. In addition, the experimental cell culture samples included those obtained from patients with inherited “mitochondrial disease” (lethal SURF1 mutations), thus providing extra experimental insights.

Obtained dataset is available publicly Here.

Link to the publication: A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations.

Health and Wellness Questionnaire

johnleddo — Sat, 04 Mar 2023 20:52:35 +0000

A lot of research is being done on things people can do to live longer
and healthier like improving their diet, exercise, taking nutritional
supplements, stress management and sleep. The challenge is that
scientists typically look at one factor at a time
in their research in order to maintain experimental control. I’m part of
a research team that’s investigating how much benefit people get from
combining different interventions and have an anonymous questionnaire on
your lifestyle that will help shed light on this.
When complete, we’ll
share the results with this group.
Thanks for your help.
https://docs.google.com/forms/d/e/1FAIpQLSfiUL756otYAywrzroTGQwE5tnRiZBLvvuuSXce4AxaiBVKng/viewform

Reply To: Just frozen vs. freeze-dried

foodie — Sat, 04 Feb 2023 23:16:12 +0000

Just add water to restore food looks

Just frozen vs. freeze-dried

foodie — Sat, 04 Feb 2023 08:13:30 +0000

While this is not easily affordable solution for every household, the freeze-dried food preservation is now available for everyone.
We all know that refrigerating and freezing food of all sorts is absolutely critical (for storage), because such measures prevent spoilage – the “bugs” don’t propagate too fast in the cold and nutrition is not “falling apart” as quickly when frozen.
However, just refrigerating an freezing may not be enough for both – longer term storage and nutritional value preservation.
Here is some “cons and pros” about freeze-drying foods at home, from professionals at Utah State university:
Buying a Home Freeze-Dryer: What to Know Before You Go

If you have scientific background

dinades — Mon, 30 Jan 2023 10:12:31 +0000

If you have any level of the scientific degree, or you feel that you are sufficiently verse on the subject, per you own research, please join our subgroup “Longevity and Aging for Scientists” (see the group’s main menu for the link – “subgroup”).
This is where the “hard core” terminology may be a common place, but this is also a place where you may “pick up” some questions to post in the main group.